Professor Datuk Dr Abd Rahman Abd Jamal


Director

MD (UKM), MRCP (Ireland), PhD (London)

PhD thesis in Haematology (awarded by University of London 1996)



BIDANG PENYELIDIKAN

• Molecular biology of cancers

Our research mainly focuses on the role of oncogenes, tumour suppressor genes, DNA repair genes in several cancers including colorectal cancer, bladder cancer and breast cancer. We also have a strong childhood leukaemia study group looking at gene arrangements, multi-drug resistance pathways as well as minimal residual disease.

• Thalassaemia

Our team focuses on morbidity and complications as well as the epidemiological aspects of the disease.

• Clinical oncology

Our team focuses on survival studies, clinical trials for febrile neutropenia and late effects of therapy.



PENERBITAN

• Hamidah A, Rashid RA, Jamal R, Zhao M, Kanegane H.X-linked dyskeratosis congenita in Malaysia. Pediatr Blood Cancer. 2008 Feb;50(2):432

• Hamidah A, Rizal AM, Nordiah AJ, Jamal R. Piperacillin-tazobactam plus amikacin as an initial empirical therapy of febrile neutropenia in paediatric cancer patients. Singapore Med J. 2008 Jan; 49(1):26-30.

• N. Fazlina, A. Maha, R. Jamal, A.L. Zarina, S.K. Cheong, A. Hamidah, O. Ainoon, S.Z. Zulkifli & N.H. Hamidah. Expression of multidrug resistance (MDR) proteins and in vitro drug resistance in acute leukemias. Hematology. 2007; 12(1):33-37

• Zarina AL, Hamidah A, Zulkifli SZ, Zulfiqar MA, Jamal R. Malignant pancreatic carcinoid tumour. Singapore Med J. 2007;48(12):e320-2.

• Hamidah A, Rashid RA, Jamal R, Zhao M, Kanegane H. X-linked dyskeratosis congenita in Malaysia. Pediatr Blood Cancer. 2007

• Hamidah A, Lim YS, Zulkifli SZ, Zarina AL, Nordiah AJ, Jamal R. Cefepime plus amikacin as an initial empirical therapy of febrile neutropenia in paediatric cancer patients. Singapore Med J. 2007 Jul;48(7):615-9.

• Nooraini MY, Zalina AZ, Raiza S, Rosita J, Suzana S, Rahman Jamal. A pilot project on the nutrition status amongst paediatric oncology patients at the Hospital Universiti Kebangsaan Malaysia. Malaysian J Health Sciences. 2007;5:47-58.

• Hamidah A, Khu SY, Thambidorai CR, Muhaizan WM, Zarina AL, Jamal R. Recurrent gastric inflammatory myofibroblastic tumour in a 13-year-old male. Pediatr Surg Int. 2006

• Sim EUH, Bong IPN, Balraj P, Tan SK, Rahman Jamal, Sagap I, Nadeson S, Rose IM, Lim PKM. A preliminary study of differentially expressed genes in Malaysian colorectal carcinoma cases. Jurnal Biosains. 2006;17:19-37

• Azian M, Hapizah MN, Khalid BAK, Khalid Y, Rosli A, Rahman Jamal. Use of denaturing gradient gel electrophoresis (DGGE) method for mutational screening of patients with Familial hypercholesterolaemia (FH) and Familial defective apolipoprotein B100 (FDB). Malaysian J Pathol. 2006;28:7-15



GERAN PENYELIDIKAN (geran penyelidikan yang sedang berjalan)

Project: The Malaysian Cohort

Source: MOSTI

Amount: RM22,493,750



Project: Eukaryotic cells in space

Source: MOSTI

Amount: RM763.000



Project: Genetics mutation and changes in expression profiles in Caeonorhabditis elegens exposed to space radiation and microgravity

Source: MOSTI

Amount: RM575,000



Project: Genetic polymorphisms and enzyme activity of thiopurine S-methyltransferase: Development of molecular diagnostics and a bioassay to reduce toxicity and enhance therapeutic efficiency in acute lymphoblastic leukaemia

Source: Sciencefund (MOSTI)

Amount: RM247,000



Project: XMEs in breast cancers and cervical cancers

Source: MOH

Amount: RM500,000



Project: Genotype-Phenotype Correlation in thalassaemia: Towards development of a lab-on-a-chip for diagnosis and prognostication

Source: Sciencefund (MOSTI)

Amount: RM242,600



Project: Genotype-Phenotype Correlation for Fragile X Syndrome: Towards a Personalised Approach for Diagnosis, Management and Rehabilitation

Source: FRGS (MOHE)

Amount: RM60,000.00



Project: Malaysian Cancer epiGenome Project: A Genome-wide Methylation Analysis of Breast and Colorectal Cancers

Source: MOSTI

Amount: RM3,224,000.00



AKTIVITI PROFESIONAL

• Interim Project Leader, Malaysian Cohort Study (MOSTI)

• Chairman, National Committee on Guidelines for Stem Cell Research

• Chairman, Expert Panel, National Thalassaemia Registry

• Member, Medical Qualifications Board, Malaysian Medical Council

• Adviser, Federation of Malaysian Thalassaemia Societies

• Treasurer, Malaysian Society of Paediatric Oncology